Two surgeons at the Careggi teaching hospital in Florence used Google Glass during an operation to extract a human liver for transplant, the Region of Tuscany said on Friday.
The digital hands-free eyewear allowed surgeons to use voice commands to view images which helped reduce the time of the surgery.
That, in turn, lessened the risk of complications as well as recording images that can later be used for teaching purposes.
The project was sponsored by the Tuscan Organization for Transplants and the Tuscan chapter of the Italian Organ Donor Association.
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