Rugby: Parisse returns as Brunel revamps Italy for England
Seven changes to starting lineup, one tactical08 March, 17:18
The Azzurri started their campaign with a stunning 23-18 win over France on the opening day.
But since then they have slumped to a 34-10 defeat in Scotland and gone down 9-26 to Wales at home, prompting Brunel to ring the changes.
Parisse, who is considered one of the world's best number eights, returns after his ban for allegedly insulting a referee while in action for his club Stade Francais was cut from 30 to 20 days in appeal.
Brunel has reinstated flyhalf Luciano Orquera, who was the man-of-the-match of the win over France but dropped to the bench after an error-strewn performance in Scotland, at the expense of Kris Burton. Gonzalo Garcia comes into the team at inside centre, with Gonzalo Canale switching to outside centre and Tommaso Benvenuti dropping to the bench.
Roberto Barbieri takes over at blindside flanker from Alessandro Zanni, fit-again Robert Barbieri starts at openside in place of Simon Favaro and Parisse replaces Manoa Vosawai at the back of the scrum.
In the second row Joshua Furno and Quintin Geldenhuys take over from Francesco Minto and Antonio Pavanello.
Prop Alberto De Marchi enters the front row with Andrea Lo Cicero demoted to the replacements.
If Lo Cicero, 36, comes on at London's Twickenham stadium he will collect his 102nd cap and become the player to have the most appearances for Italy of all time.